A suicide bomber on a motorbike rammed through a marketplace outside a Shia religious seminary, in northwestern Orakzai district near the border with Afghanistan on Friday, killing at least 30 people, including members of minority Sikh community.
Over 50 people were injured in the terror attack targeted at Shias, the minority sect in the Sunni Muslim-majority Pakistan.
Abbas Khan, a senior district management official said, "A suicide bomber drove a motorcycle into a crowd busy in shopping at a weekly festival (Juma Bazar) before detonating his explosives."
Among the dead were three members of the minority Sikh community and two security officials, he added.
"The majority of the dead were Shia," Aminullah, an official of local administration said adding that at least 51 people were injured, 17 of them critically.
The injured have been shifted to hospitals in Kohat and Peshawar.
The suicide attack took place outside an imambarah (a religious seminary of Shia Muslims) in Kalaya Bazar, a Shia majority area in Lower Orakzai district.
Lower Orakzai was one of the tribal agencies before its merger into Khyber Pakhtunkhwa province by the previous government.
Prime Minister Imran Khan and his minister for Human Rights, Shireen Mazari, condemned the attack.
In a tweet, Mazari feared that the death toll could rise and blamed the US failures in neighbouring Afghanistan for the attack.
"As the US fails in Afghanistan, Pakistan should be prepared for a fallout and we must ensure greater security for our tribal areas especially protection of our people," Mazari tweeted.
The attack occurred shortly after a brazen attack on the Chinese consulate in Karachi by members of the Balochistan Liberation Army (BLA), a militant group of ethnic Baloch separatists that had waged a nationalist insurgency against the Pakistani state.
The BLA attack left two police officers and two civilians dead. No group has yet claimed responsibility for the Orakzai bombing.